#2021台灣生技論壇(Taiwan Biotech Forum)由我來開幕致詞,歡迎您一同在線上共襄盛舉!
摘錄:「儘管這一年多來,全世界都受到 COVID-19 的威脅,但台灣從一開始的病例數就比鄰國更低,我認為這是我們政府、醫療保健系統、學術研究機構,以及像生技中心的生物技術單位所共同努力的結果,這就是我所說的『快速專業做防疫』。」
(Although the world has been under the threat of COVID-19 more than one year, Taiwan has relatively fewer cases than the other neighboring countries from the beginning; I think this is the result of many joint collaborative efforts by our government, healthcare system, academic and research institutes, as well as our biomedical sector. This is what I called “Fast and Expert Action”.)
「2021台灣生技論壇主題為『為下一次大流行而準備:預備,設定,出發!』聚集台灣乃至全球公共衛生、人工智能、醫藥、治療、法律等領域的代表性人物。這些主題演講將回顧我們從大流行中學到的經驗,並前瞻未來所需的改進之道。」
(2021 Taiwan Biotech Forum themed “Preparing for the Next Pandemic: Ready, Set, and Go!” gathered the leading minds in the fields of public health, AI, pharmaceuticals, therapeutics and law from Taiwan and the world. The topics will look back on what we have learned from pandemic and also looking forward to review the enhancement needed for the future.)
🔔 主題演講:
1️⃣ 陳建仁 中央研究院基因體研究中心院士 | Taiwan’s Experience and Preparations for Future Emerging Infectious Disease
2️⃣ Toru Jay Seo 輝瑞(Pfizer)亞太區負責人暨資深總監 | Life Science Industry in Post-COVID-19 Era
3️⃣ 林清詠 美商圖策智能科技有限公司(Graphen)執行長 | Advancing Full-Brain AI Technologies for Drug Development and Genome Analysis
4️⃣ Philip Tagari 安進(Amgen)全球研發副總裁 | Real-time Therapeutics Discovery
5️⃣ Shaun Grady 阿斯特捷利康(AstraZeneca)全球商務發展營運資深副總裁 | Innovation and Partnerships in Post-Covid Era
6️⃣ 劉秉彥 成大醫院臨床醫學研究中心主任校園 | A Milestone in the QurE “m.Cov-tainer” in NCKU Campus
7️⃣ 張文貞 國立陽明交通大學科技法律學院院長 | COVID-19 and Human Rights: Taiwan’s Experience
📽 完整影片快看 | https://youtu.be/sq5rrPZ8qFU
同時也有4部Youtube影片,追蹤數超過1,460的網紅Sammy LYN,也在其Youtube影片中提到,✅本集資訊 昆士蘭大學 The University of Queensland 生物醫學系 Biomedical Science Jennifer's YouTube: @Im Jennifer ➡️這是我的IG啦 : _sammylyn_overseas_ ➡️這是我的FB啦 : Sammy...
「biomedical science」的推薦目錄:
- 關於biomedical science 在 涂醒哲 Dr.Twu Facebook 的最佳貼文
- 關於biomedical science 在 可貓all cat Facebook 的精選貼文
- 關於biomedical science 在 Scholarship for Vietnamese students Facebook 的精選貼文
- 關於biomedical science 在 Sammy LYN Youtube 的最佳貼文
- 關於biomedical science 在 Ariel Yeung Youtube 的最佳解答
- 關於biomedical science 在 Ariel Yeung Youtube 的最佳貼文
biomedical science 在 可貓all cat Facebook 的精選貼文
疫情嚴重,注意健康,加油
2019-2020相關資料文獻整理
#新型冠狀病毒和黑種草油的科學研究
2019-nCoV & Nigella Sativa Science
Researches
#林博士聲明: 2020.01.28
1.本文為本人整理編寫的原創文獻醫學文稿,重要內容均注明原文出處(或網路連結)若有疏漏,敬請指正。
(一)#抗病毒作用-正義單鏈RNA病毒
Antiviral effect-positive and single stranded RNA virus
- 2019新型冠狀病毒(Novelcoronavirus),世界衛生組織命名縮寫為2019-nCoV、武漢肺炎(Wuhanpneumonia)等。2019新型冠狀病毒與2003年4月在亞洲爆發SARS,SARS-CoV都是正義單鏈RNA病毒(positivesinglestrandedRNAvirus),這類病毒還包括人類的C型肝炎病毒(HepacivirusC)。
黑種草油(子)迄今並無抗冠狀病毒的研究。但臨床研究顯示黑種草油可以抗C型肝炎病毒(30名C肝病患),降低體內病毒載量。
埃及30名患有C型肝炎病毒(HCV)感染患者,未經甲型干擾素(α-Interferon)治療,每天餐後食用黑種草油,每日3次,連續服用3個月後,可顯著改善HCV病毒載量(380808.7±610937vs147028.2±475225.6,P=0.001)和提高體內總抗氧化能力TAC(1.35±0.5vs1.612±0.56, P=0.001),與下列實驗室參數得到改善:總氮蛋白、白蛋白、紅血球細胞數、血小板計數和下肢水腫等臨床狀況指數。
1.Barakat, EmanMahmoud Fathy, Lamia Mohamed El Wakeel, and RadwaSamir Hagag. "Effects of Nigella sativa on outcome of hepatitis C in Egypt." World journal of gastroenterology: WJG 19.16 (2013): 2529.
2.Oyero, OlufunmilayoG., et al. "Selective inhibition of hepatitis c virus replication by Alpha-zam, a Nigella sativa seed formulation." African journal of traditional, complementary and alternative medicines 13.6 (2016): 144-148.
(二) #免疫調節-提高巨噬細胞和樹突狀細胞作用.
*Immunomodulatory effects
- 研究顯示:黑種草油或其活性成分百里醌(TQ,Thymoquinone)可以調節免疫力(Th1和Th2),提高巨噬細胞(macrophage)和樹突狀細胞(dendriti)作用,顯示出有效的抗發炎作用。
黑種草油可增加吞噬活性(吞噬率56.83±6.37%)和吞噬指數(5.18±0.39),巨噬細胞分泌IL-12(最高水平在66.33±2.11μM)和TLR4的表達。數據通過單因子變異數分析(One-wayANOVA)進行統計學檢驗,顯著性為95%。
1.Akrom, Akrom, and MustofaMustofa. "Black cumin seed oil increases phagocytic activity and secretion of IL-12 by macrophages." Biomedical Research 28.12 (2017): 5241-5246.
2.Finlay, Trisha M., et al. "Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo." Glycoconjugate journal 27.6 (2010): 583-600.
3.Salem, Mohamed Labib. "Immunomodulatory and therapeutic properties of the Nigella sativa L. seed." International immunopharmacology 5.13-14 (2005): 1749-1770.
(三) #善肺部發炎症狀和損傷
Improve lung inflammation and injury
- 動物研究顯示:黑種草和其提取物或百里醌(TQ)對氣管反應和肺部炎症有預防作用,黑種草油可顯著降低因高氧吸入引起的肺損傷。
●黑種草的百里醌(TQ,thymoquinone)治療致敏組動物,可顯著善其肺部病理變化,降低其IL-4水平(p<0.05至p<0.001),增加其IFN-γ水平(p<0.001)。
●黑種草治療可抑制炎症性肺反應,顯著降低(p<0.05)支氣管周炎性細胞浸潤、肺泡中隔浸潤、肺泡水腫 肺泡滲出液、肺泡巨噬細胞和間質纖維化,肉芽腫和壞死形成。
●在組織病理學和免疫化學評估中,高氧+ 黑種草組的肺損傷嚴重程度明顯降低(P <.05),GSH-Px(穀胱甘肽氧化物酶)和SOD(超氧化物歧化酶)水平得到顯著保留MDA(血清脂質過氧化物)和MPO(骨髓過氧化酶)水平顯著低(P <.05)。
1.Boskabady,MohammadHossein,etal."TheeffectofNigellasativaextractontrachealresponsivenessandlunginflammationinovalbumin-sensitizedguineapigs."Clinics66.5(2011):879-887.
2.Keyhanmanesh,Rana,etal."Effectofthymoquinoneonthelungpathologyandcytokinelevelsofovalbumin-sensitizedguineapigs."Pharmacologicalreports62.5(2010):910-916.
3.Kanter,Mehmet."EffectsofNigellasativaseedextractonamelioratinglungtissuedamageinratsafterexperimentalpulmonaryaspirations."Actahistochemica111.5(2009):393-403.
4.Tayman,Cuneyt,etal."ProtectiveeffectsofNigellasativaoilinhyperoxia-inducedlunginjury."ArchivosdeBronconeumología(EnglishEdition)49.1(2013):15-21.
(四) #解呼吸道發炎症狀
Relief the symptoms of respiratory tract infection
- 多篇人體臨床研究:黑種草油可顯著緩解咽喉炎或扁桃腺炎的咽喉腫痛,補充黑種草油可改善哮喘和肺功能。黑種草的精油成分可抑制氣管收縮和增加黏膜纖毛的清除率。
●186位急性咽喉炎測試者,每天3次連續7天服用黑種草油和珠草萃取物,可完全緩解他們的咽喉腫痛,減少對止痛藥的需要。
●抗效喘和擴張氣管
80名哮喘患者的隨機,雙盲,安慰劑對照試驗,每天食用黑種草油兩次,連續4週,NSO組的平均哮喘控制測試得分顯著提高了21.1(標準差= 2.6)和19.6(標準差= 3.7)(p = 0.044),血液中的嗜酸性粒細胞減少了-50 (-155至-1)對15(-60至87)個細胞/μL(p = 0.013)。
29例哮喘成年患者隨機分為對照組和研究組,研究組給予每天口服黑種草提取
物,研究3個月後顯著改善哮喘症狀的頻率/週,胸部喘息和肺功能測試(PFTs)
值顯著改善(P <0.05到P <0.001),與對照組相比有顯著差異(P <0.01到P <0.001)。
在15例哮喘患者,黑種草萃取物對哮喘的氣道(airways)具有相對強效的抗喘效果(支氣管擴張)。
●天然氣管擴張劑,抑制氣管收縮和增加黏膜纖毛的清除2010年歐洲藥用植物和天然產品研究雜誌《Planta Medica》研究:黑種草的精油活性成分-百里醌(TQ) 、黑種草酮(Nigellone)是優於哮喘的吸入性氣管擴張藥fluticasone(屬類固醇類),賦予哮喘和過敏症患者帶來希望。
2008年歐洲藥用植物和天然產品研究雜誌《Planta Medica》研究表明:黑種草油的精油成分黑種草酮(Nigellone)和百里醌(TQ)可用於治療不同的呼吸系統疾病,可緩解氣管的痙攣和增加黏膜纖毛的清除率。
1.Dirjomuljono, M., et al. "Symptomatic treatment of acute tonsillo-pharyngitis patients with a combination of Nigella sativa and Phyllanthus niruriextract." International journal of clinical pharmacology and therapeutics 46.6 (2008): 295-306.
2.Koshak, Abdulrahman, et al. "Nigella sativa supplementation improves asthma control and biomarkers: A randomized, double‐blind, placebo‐controlled trial." PhytotherapyResearch 31.3 (2017): 403-409.
3.Boskabady, Mohammad Hossein, et al. "The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients." Fundamental & clinical pharmacology 21.5 (2007): 559-566.
4.Boskabady, M. H., N. Mohsenpoor, and L. Takaloo. "Antiasthmaticeffect of Nigella sativa in airways of asthmatic patients." Phytomedicine 17.10 (2010): 707-713.
5.Keyhanmanesh, Rana, et al. "The effect of thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs." Planta medica 76.03 (2010): 218-222.
6.Wienkötter, N., et al. "The effect of nigelloneand thymoquinone on inhibiting trachea contraction and mucociliaryclearance." Planta medica 74.02 (2008): 105-108.
#薑黃文獻研究
●#薑黃的薑黃素抑制所有C型肝炎病毒基因型進入人肝細胞
Colpitts, Che C., et al. "Turmeric curcumin inhibits entry of all hepatitis C virusgenotypes into human liver cells." Gut 63.7 (2014): 1137-1149
●#薑黃素在病毒性急性呼吸窘迫綜合症的老鼠模中,調節發炎症反應並抑制隨後的纖維化
Avasarala, Sreedevi, et al. "Curcumin modulates the inflammatory response and inhibits subsequent fibrosis in a mouse model of viral-induced acute respiratory distress syndrome." PloSone 8.2 (2013).
●#薑黃素通過減輕肺損傷和調節巨噬細胞細胞因子產生來減輕嚴重的流感性肺炎
Han, Shuguang, et al. "Curcumin ameliorates severe influenza pneumonia via attenuating lung injury and regulating macrophage cytokines production." Clinical and Experimental. Pharmacology and Physiology 45.1 (2018): 84-93.
#蜂蜜文獻研究
●2014年一項基於前瞻性隊列研究:以蜂蜜做保守療,35%的慢性C型肝炎病毒患者可持續清除C肝炎病毒
KOTB, MAGD A., and AHMED K. ABDALLA. "Sustained Hepatitis C Virus Clearance was Achieved by Honey Based Conservative Management in 35% of Chronic Hepatitis C Virus Patients: A Prospective Cohort Study." Interferon 8: 10.
●蜂蜜與健康:近期臨床研究述評-蜂蜜具抗發炎免疫調節活性、減少咳嗽、發燒和減輕哮喘相關症狀
Samarghandian, Saeed, TaherehFarkhondeh, and FariborzSamini. "Honey and health: A review of recent clinical research." Pharmacognosy research 9.2 (2017): 121.)
#食用建議
#黑種草油5ml + #蜂蜜10ml +#薑黃粉(#或薑黃素)適量
❗每日2次❗
#黑種草油、#蜂蜜和薑黃
都有抗單股RNA病毒、抗發炎、減少肺部發炎症狀,調節免疫力和增加抵抗力的效果,非常適合這個季節做為每日保健的補充劑。
biomedical science 在 Scholarship for Vietnamese students Facebook 的精選貼文
[Tổng hợp] Tất tần tật học bổng, sự kiện, lớp học cho bạn tham gia tháng 5!
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biomedical science 在 Sammy LYN Youtube 的最佳貼文
✅本集資訊
昆士蘭大學 The University of Queensland
生物醫學系 Biomedical Science
Jennifer's YouTube: @Im Jennifer
➡️這是我的IG啦 : _sammylyn_overseas_
➡️這是我的FB啦 : Sammy LYN 海外報
🇦🇺澳洲留學資訊
看這一個就夠!!!雅思準備全攻略(附上我的應考筆記) https://youtu.be/gXLted0x_uU
我的澳洲學生宿舍 + room tour!!!! https://youtu.be/46C-P5BR3PU
如何申請澳洲大學!? 免學測、指考超簡單攻略!!!! https://youtu.be/nxQimEi86QU
澳洲學生宿舍宛如高級飯店!!! 超詳細房間+公共設施介紹~ https://youtu.be/hj_v-wwhfTA
澳洲找住宿?便宜的學生宿舍?給菜鳥留學生的意見 https://youtu.be/yAe33HWkAzw
澳洲留學花費大公開🇦🇺!!! 留學是個天價啊啊!!! 喝珍奶真的好奢侈😭 https://www.youtube.com/watch?v=ql5Pi_ayh_s
部分圖片取自google
Photo by Ondrej Machart on Unsplash
Music used:
Music by frumhere, kevatta - warm feeling - https://thmatc.co/?l=3A5F9247
contact: sammylyn19@gmail.com
This video is not sponsored
biomedical science 在 Ariel Yeung Youtube 的最佳解答
Hi, my name is Ariel. If you’re new I make videos to spread the joy and memories. Make sure to subscribe to my channel and hit the notification bell, so whenever I post, you will get a notification on the newest video I post.
You can reach me my Instagram DM : @ariely.hk.kn
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Australian university unbiased youtube review by Mr Rob. Malicki : https://www.youtube.com/channel/UCjtCSG3vwgoLfZYGTquyoOA (HIGHLY RECOMMENDED IF YOU'RE CONSIDERING TO STUDY IN AUSTRALIA)
biomedical science 在 Ariel Yeung Youtube 的最佳貼文
Hi, my name is Ariel. If you’re new I make videos to spread the joy and memories. Today is the first day for university classes. I got offered to study semester 2 at the University of Queensland from high school. If anyone is curious, I am currently an undergraduate student doing a double degree which is Bachelor of Biomedical Sciences and Bachelor of science. So, if you're interested to know what my first day at university online went. Go ahead and watch this video and hope you enjoy it.
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Background music: Music by ninjoi. - Passin [Thematic Exclusive] - https://thmatc.co/?l=FF3E2728
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IG: ariely.hk.kn
Email: kpgirl37@gmail.com
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